17 Science-Backed Natural Remedies for Headaches
Evidence based tips to treat headaches safely and effectively.
Author: MaryAnn DePietro CRTSTART READING
According to the World Health Organization, 40% of the global population is affected by headaches (3.1 billion people). Additionally, migraines alone rank as the third leading cause of neurological disability worldwide. It's clear that headaches are a core issue amongst the general population.
How can headaches be effectively treated?
WHO also reported that nearly half of those with headache disorders are self-treating. Additionally, they're utilizing medications for treatment. These medications run the risk of 'medication-overuse headaches,' which can affect up to 5% of some populations.
A holistic approach is key to effective headache treatment, emphasizing natural, safe methods that typically have fewer side effects than medications. This article explores study-backed holistic methods shown to help certain headache types in some individuals.
Immediate Relief (The "Right Now" Toolkit)
Most people will experience a headache at some point. Headaches could range in severity from bothersome to debilitating.
The faster the pain is eased, the sooner daily activities can resume. Not everyone chooses medication for relief. Fortunately, non-pharmaceutical techniques can be used to stop an active headache.
Non-pharmaceutical techniques to stop a headache are designed to target common triggers without medication. These methods have been found to be effective for some people by addressing triggers such as nerve irritation, blood vessel dilation, dehydration, overstimulation, and muscle tension.
A primary rule when using non-pharmaceutical techniques is to combine mechanical techniques (i.e., TENS therapy) with sensory adjustments (i.e., a dark environment).
These natural remedies for headaches are thought to work by disrupting how your brain interprets pain signals. Non-pharmaceutical techniques may also help regulate blood flow without causing the rebound effect sometimes seen with OTC medication, though effectiveness can vary between individuals and headache types.
Mechanical & Physical Interventions
Mechanical and physical interventions can help combat headaches, including those listed below.

TENS Therapy
Transcutaneous electrical nerve stimulation (TENS) is a drug-free treatment. It uses a small device to send mild electrical currents through the skin to reduce pain. TENS works by interfering with pain signals traveling to the brain. This effect is described by the gate control theory, and some studies suggest TENS may be effective for certain headache sufferers.
The theory is that the spinal cord acts as a “gate,” allowing or blocking pain signals from reaching the brain. The gate is a functional process, not a physical structure. Nerve cells interact to control pain signals before they reach the brain. These cells can regulate whether pain is increased, reduced, or blocked.
TENS works by preventing pain signals from reaching the brain. Placing electrodes on the base of the neck (the trapezius muscle) can “scramble” pain signals and reduce headache pain.
TENS therapy may also stimulate endorphin release, a natural pain chemical, and promote blood flow to the area, relaxing muscles and reducing tension headaches. At-home TENS therapy has been reported by some to be a beneficial non-invasive treatment option for migraines and tension headaches, though results may vary.

Thermal Regulation
Thermal regulation can include applying a cold compress to relieve headaches in some individuals, potentially causing vasoconstriction for natural pain relief.
Vasoconstriction is the narrowing of the blood vessels, which may temporarily numb pain-sensitive nerves. Use of a cold compress tends to be most effective for migraines in some people, but placement and results may require trial and error.
Placement locations for a migraine include:
- Apply a cold pack to the temples to cool the trigeminal nerve branches.
- Place an ice pack on the base of the skull to target the occipital nerves. This technique may provide relief for some individuals.
- Use a special migraine ice wrap to encircle the entire head, as this may decrease nerve sensitivity for those who find it effective.

Warm Compresses/Baths
Taking a warm bath or placing a warm compress on the head or neck can be beneficial for some types of headaches. The heat can induce vasodilation, improving blood flow, reducing tension, promoting relaxation, and decreasing nerve irritation. This approach seems especially effective for tension and cervicogenic headaches in some people.
A cervicogenic headache starts in the neck and moves to the head. Your cervical spine shares the same nerve pathways with the head, so the brain may interpret neck pain as a headache.
Placing a warm compress on the neck or the back of the head can relieve muscle tightness. Limited research is available on the ideal temperature for warm compresses. However, most experts agree that a range of 104°F to 110°F is likely effective without risking a burn.
Reusable hot and cold compresses are a good option since some people respond better to heat and others to ice, depending on personal triggers and headache type.
Pressure Management
Remove tight ponytails, headbands, and hats that put pressure on the head. Excessive tightness may irritate facial nerves, leading to neck tension and potential tension headaches.

Massage & Acupuncture
Another effective natural headache remedy is massage and acupuncture. Massage can promote relaxation, reduce tension, and stimulate blood flow. When applied to the upper shoulders and neck, it can help reduce a cervicogenic headache.
Acupuncture, particularly targeting the:
- LI4 (Hegu) point
- And the occipital ridge at the base of the skull
can stimulate sensory nerves, reducing pain signaling in some individuals.
Preventative & Long-Term Strategies
It's not only important to treat a headache, but it's also essential to develop long-term prevention strategies.
Making certain lifestyle and metabolic adjustments involves daily habits that help your nervous system become more resilient. This can raise your headache threshold. Simply put, it makes you more resilient to triggers such as stress that can set off a headache. By strengthening your baseline, common triggers are less likely to lead to a headache.
With all preventive strategies, it's important to maintain consistency in your sleep schedule, diet, and supplementation. The ideal timeline is 3 months to give them time to work.
Lifestyle habits and metabolic adjustments can reduce systemic inflammation and stabilize neuronal excitability, thereby reducing the likelihood of headaches.
Reduced inflammation means fewer inflammatory chemicals circulate, which can reduce pain signaling. Stabilizing neuronal excitability means a calmer brain. Pain pathways are less reactive, and neurotransmitters like serotonin stay balanced.
The Metabolic Foundation (Supplements)
Supplements can act as natural pain relievers for headaches or as preventive strategies. Consider the following:
Magnesium
Specifically, magnesium glycinate has superior bioavailability. Magnesium supports calming neurotransmitters, and it may help raise the headache threshold needed to trigger a migraine.
Riboflavin (B2)
B2 is critical for mitochondrial energy production in brain cells. The more energy-stable the brain is, the less likely it is to develop a migraine.
Coenzyme Q10
This is a powerful antioxidant for neuroprotection. That means it may protect the brain cells and blood vessels. This helps neutralize free radicals and reduce irritation and pain pathways.
Feverfew & Ginger
These supplements are botanical inhibitors of prostaglandin biosynthesis. Prostaglandins are chemicals that promote inflammation in the body. They can alter blood vessels and sensitize pain receptors. Supplements that inhibit prostaglandin production can help reduce headaches, especially migraines.
Lifestyle & Hygiene
Natural remedies for headaches include lifestyle hygiene, such as the following:

Sleep Hygiene
Maintain a consistent wake/sleep cycle to prevent "weekend migraines." This can develop if your sleep schedule becomes inconsistent on the weekends, such as going to bed later. Inconsistent sleep leads to irregular melatonin release, disrupted cortisol timing, and serotonin fluctuations. Pain pathways can become more sensitive, triggering a migraine.
Many headaches can also have an ergonomic root cause. This can include poor posture when sitting, which can put excess tension on the shoulders and neck. Your sleep posture can also increase your risk of a headache.
Good sleep posture keeps your spine in a neutral position from your neck to your lower back. A good orthopedic pillow for headache prevention can:
- Help keep you in proper alignment.
- And promote a restful night's sleep.
Regular Exercise
Aerobic activity releases endorphins, our body's natural "opioid-like" pain relievers. Aim to get 30 minutes of moderate to intense exercise on most days of the week.
Dietary Management
For some people, eating certain foods can trigger migraines. Two of the most common biochemical triggers include tyramine and nitrate. Common foods that contain tyramine include soy sauce, blue cheese, and alcohol. Foods that contain nitrates to watch out for include hot dogs, deli meats, and bacon.
Consider tracking these foods to determine if they could be a potential cause of your headaches. It's also helpful to eat regular meals containing healthy fats and protein. These help stabilize blood sugar and avoid hunger headaches.
Stress Management
Stress is a major trigger of headaches, especially tension headaches. Consider practicing stress management techniques such as deep breathing or biofeedback to:
- Lower cortisol levels
- Reduce muscle guarding
- And promote relaxation.
Headache Red Flags
Most headaches are treatable with some of the home remedies listed above. However, in certain instances, a headache can indicate something more serious.
For example, a thunderclap headache. This is a severe headache with sudden onset, lasting about 5 minutes, and peaking within 60 seconds. People who experience a thunderclap headache often describe it as the worst headache of their lives.
Any severe headache that starts suddenly should be checked right away. This helps rule out serious emergencies like a brain aneurysm.
According to the Mayo Clinic, additional headache red flags that require immediate medical attention include:
- Confusion
- Stiff neck
- Trouble seeing or speaking
- Fainting
- Numbness and paralysis on one side of the body
About the Author

MaryAnn DePietro CRT is a licensed respiratory therapist with over 15 years of clinical experience in critical care, emergency medicine, and pulmonary rehabilitation. She is also an American Council on Exercise certified personal trainer and holds specialty certifications in orthopedics, senior fitness, and weight management. MaryAnn has a degree in Rehabilitation from Penn State University and a degree in respiratory therapy.
In addition to her clinical experience, she has written extensively about all things medical, as well as health, fitness, and aging for various websites, magazines, and newspapers.
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